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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
MARK2
All Species:
6.06
Human Site:
S380
Identified Species:
11.11
UniProt:
Q7KZI7
Number Species:
12
Phosphosite Substitution
Charge Score:
-0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q7KZI7
NP_001034558.2
788
87911
S380
I
T
L
K
P
R
P
S
A
D
L
T
N
S
S
Chimpanzee
Pan troglodytes
XP_001172839
796
89049
C387
S
L
S
S
G
N
L
C
Q
R
S
R
P
S
S
Rhesus Macaque
Macaca mulatta
XP_001115591
788
87964
S380
I
T
L
K
P
R
P
S
A
D
L
T
N
S
S
Dog
Lupus familis
XP_540890
798
88683
P399
T
I
T
L
K
P
R
P
S
A
D
L
T
N
S
Cat
Felis silvestris
Mouse
Mus musculus
Q05512
776
86287
P377
G
D
T
I
T
L
K
P
R
P
S
A
D
L
T
Rat
Rattus norvegicus
O08679
722
80853
R327
L
P
D
Y
K
D
P
R
R
T
E
L
M
V
S
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001511751
793
88836
C386
S
M
S
S
G
N
L
C
L
R
S
R
P
S
S
Chicken
Gallus gallus
Q9IA88
798
88848
S381
M
P
Q
D
S
L
T
S
E
T
L
R
S
S
L
Frog
Xenopus laevis
NP_001080425
785
87931
P384
L
T
L
K
P
R
P
P
P
D
I
S
N
S
I
Zebra Danio
Brachydanio rerio
Q6NSM8
1187
130949
P475
Q
K
L
A
P
G
F
P
R
V
A
P
Q
A
P
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Q9TW45
1192
126331
Q497
A
S
E
I
T
M
A
Q
S
L
L
S
H
S
S
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
P92958
512
58671
Q116
I
V
E
K
G
R
L
Q
E
D
E
A
R
N
F
Baker's Yeast
Sacchar. cerevisiae
P06782
633
72027
C238
P
E
V
D
V
W
S
C
G
V
I
L
Y
V
M
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
68.2
99.7
95.1
N.A.
96.6
89.9
N.A.
68.4
30.3
84.3
27.5
N.A.
N.A.
N.A.
38.8
N.A.
Protein Similarity:
100
80.4
99.7
96.2
N.A.
97.7
90.9
N.A.
80.5
48.7
91.7
42.7
N.A.
N.A.
N.A.
49.9
N.A.
P-Site Identity:
100
13.3
100
6.6
N.A.
0
13.3
N.A.
13.3
20
60
13.3
N.A.
N.A.
N.A.
20
N.A.
P-Site Similarity:
100
13.3
100
20
N.A.
13.3
20
N.A.
13.3
33.3
80
20
N.A.
N.A.
N.A.
46.6
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
26.5
27.5
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
44.1
45.5
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
26.6
0
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
33.3
13.3
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
8
0
0
8
0
0
8
0
16
8
8
16
0
8
0
% A
% Cys:
0
0
0
0
0
0
0
24
0
0
0
0
0
0
0
% C
% Asp:
0
8
8
16
0
8
0
0
0
31
8
0
8
0
0
% D
% Glu:
0
8
16
0
0
0
0
0
16
0
16
0
0
0
0
% E
% Phe:
0
0
0
0
0
0
8
0
0
0
0
0
0
0
8
% F
% Gly:
8
0
0
0
24
8
0
0
8
0
0
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
8
0
0
% H
% Ile:
24
8
0
16
0
0
0
0
0
0
16
0
0
0
8
% I
% Lys:
0
8
0
31
16
0
8
0
0
0
0
0
0
0
0
% K
% Leu:
16
8
31
8
0
16
24
0
8
8
31
24
0
8
8
% L
% Met:
8
8
0
0
0
8
0
0
0
0
0
0
8
0
8
% M
% Asn:
0
0
0
0
0
16
0
0
0
0
0
0
24
16
0
% N
% Pro:
8
16
0
0
31
8
31
31
8
8
0
8
16
0
8
% P
% Gln:
8
0
8
0
0
0
0
16
8
0
0
0
8
0
0
% Q
% Arg:
0
0
0
0
0
31
8
8
24
16
0
24
8
0
0
% R
% Ser:
16
8
16
16
8
0
8
24
16
0
24
16
8
54
54
% S
% Thr:
8
24
16
0
16
0
8
0
0
16
0
16
8
0
8
% T
% Val:
0
8
8
0
8
0
0
0
0
16
0
0
0
16
0
% V
% Trp:
0
0
0
0
0
8
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
8
0
0
0
0
0
0
0
0
8
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _